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Complete Information on Chronic Myelogenous Leukemia
Chronic myeloid leukemia (CML), too known as chronic myelogenous leukemia. Chronic myelogenous leukemia (CML) is a slow-growing cancer of the light-colored blood cells. It is too sometimes called chronic myeloid, chronic granulocytic or chronic myelocytic leukemia. CML is a popular leukemia. In the United States, much than 20,000 folk have CML and about 4,600 original cases are diagnosed each year. Most cases of CML seem in adults, but about 2 to 4% of CML patients are children. CML is an acquired irregularity that involves the hematopoietic stalk cubicle.
It is characterized by a cytogenetic aberration consisting of a reciprocal translocation between the long arms of chromosomes 22. The translocation results in a shortened chromosome 22, an observation first described by Nowell and Hungerford and subsequently termed the Philadelphia (Ph) chromosome after the city of discovery. Early signs and symptoms of CML are often vague. They may include fever , losing weight without trying , loss of appetite and Feeling run-down or tired , pain or fullness below the ribs on the left side and sweating excessively during sleep (night sweats). Chronic myelogenous leukemia is a rare form of leukemia.
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